1971 Ankara doğumluyum. İlk ve orta öğrenimimi Isparta'da tamaladım.
1988-1995 yılları arası Hacettepe Üniversitesi Tıp Fakültesi(İng.)'ni derece ile tamamladım.
1995-2000 yılları arası Zekai Tahir Burak Kadın Hastalıkları ve Doğum hastanesinden Kadın Hastalıkları ve Doğum ihtisası aldım.
Halen Etimesgut Belediyesi Sağlık merkezinde ve kendi özel kliniğimde Uzmanlık alanımda mesleğimi icra etmekteyim.
Basılı Kitap ve Yayınları :
Mine S. Kermallİ*, Serdar Oğuz*, Nuri DanIşman*, Oya Gökmen*
* Dr., Dr.Zekai Tahir Burak Kadın Sağlığı Eğitim ve Araştırma Hastanesi, ANKARA
Objective: To compare the differences in feto-maternal infection rates and cost-effectivity of different administration of antibiotic prophylaxis in patients with premature rupture of membranes.
Materials and Methods: We randomly selected two group of patients with premature rupture of membranes whose gestational ages ranged between 26-35 weeks. Group 1 (n=54) received 4 gram of ampicillin until delivery. Group 2 (n=51) received 4 gram of ampicillin only for 48 hours and if there was no delivery, antibiotic prophylaxis was repeated for a 48 hour period with 7 day intervals at the same time with the dexamethasone (24 mg in 4 divided doses for 48 hours) administration. During the expectant management in the hospital and after delivery, both mothers and newborns were evaluated in aspects of infectious complications, perinatal morbidity and mortality, cesarean rates and cost effectivity of the treatment.
Results: We observed no differences in neonatal infection rates and perinatal morbidity and mortality between two groups. There was an increased percentage of maternal infections, especially with opportunistic microorganisms in the continuous antibiotic prophylaxis group and cesarean rate was significantly higher in this group (p<0.05). Moreover, the cost of continuous antibiotic prophylaxis was three folds higher than the intermittant antibiotic prophylaxis (p<0.001).
Conclusion: We conclude that continuous antibiotic prophylaxis in PPROM does not improve the outcome and it is cost ineffective. Intermittant and short-term antibiotic prophylaxis is preferable than the continuous antibiotic prophylaxis in PPROM patients.
Keywords: Preterm premature rupture of membranes, Antibiotic prophylaxis
Basılı Kitap ve Yayınları : 
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